The leader's 2-1 loss at home to relegation-threatened Crystal Palace on Saturday provided an unexpected twist to a title race that most observers thought was virtually over, with Chelsea holding a 10-point lead and in seemingly unstoppable form. Then, Andrea Ranocchia scored his first goals for the club in the 85 minute as Hull City still have a chance of avoiding relegation.
Meanwhile for Pep Guardiola's visitors, with January addition Gabriel Jesus sidelined, Sergio Aguero will continue to spearhead City's attack, having netted 26 times in all competitions this campaign.
After a slow start, the Premier League champions took the lead in spectacular fashion after 25 minutes when Wilfred Ndidi fired into the top corner from around 30 yards out, giving Lee Grant no chance.
Chelsea host Manchester City, while Arsenal face West Ham and Tottenham travel to Swansea on Wednesday night, following Manchester United's game with Everton on Tuesday. But I always said that the league only finishes when it is mathematically sure you have won.
Cesc Fabregas scored the opener for Chelsea in the fifth minute of the game.
Chelsea failed to avoid defeat against Palace despite boasting a close to full-strength team and having nearly 80 minutes in which to turn the game around.
Crystal Palace's Wilfried Zaha, right celebrates after scoring his side's first goal during the English Premier League soccer match between Chelsea and Crystal Palace at Stamford Bridge stadium in London Saturday, April 1, 2017.
The Crystal Palace winger was twice capped in England senior friendlies but opted to switch his allegiance to Ivory Coast - the nation of his birth - in November. We must keep playing like we have in the last four games because we are not safe yet.
"Obviously we weren't scared but we were well prepared and if you come away with three points, especially with the way we played in the second half, we can be very proud of ourselves". If we had won we would have been happy, but now we must focus on Manchester City.
Allardyce also said, in what might have been a dig at his predecessor, Alan Pardew, that he has empowered the coaches around him to improve the players.
"If someone else deserves to win the title it means that they have played better than us. I think we are a strong team". "We want to keep this position".