Geraint Thomas understandably cut a frustrated figure at the end of stage nine at the Giro d'Italia after his general classification hopes were dented by a stray police motorbike.
A police motorbike had pulled to the left side of the road on the approach to the concluding 13.6km ascent of Blockhaus.
The Team Sky rider went into Sunday's stage second overall and was well placed heading into the day's final climb when he was sent sprawling on the tarmac. My shoulder popped out as well.
Quintana stamped his authority on the Giro when he claimed the overall lead by winning the first big mountain stage, while defending champion Vincenzo Nibali was dealt a big knock when he cracked on the climb.
Quintana finished 24 seconds ahead of second-placed Pinot and Tom Dumoulin (Team Sunweb), with Nibali slipping back to finish one minute behind.
Nairoman, who has said he aims to win this year's Tour de France, the most prestigious cycling race of all, has shown the world and his rivals he is in excellent condition to do just that. I crashed in a downhill with about 35km to go. "The whole team was strong and I was strong".
Astana's Luis Leon Sanchez was third, 10 seconds further adrift, and the fourth rider of the group Valerio Conti of UAE-Emirates crashed taking a corner.
Quintana dedicated his victory to 2011 Giro champion Michele Scarponi, who died after a collision with a van while training last month.
Thomas was able to resume the race, but as Nairo Quintana stretched away atop Blockhaus, the Welshman could only come home five minutes down - all but ending his GC chances.
Team Sky's Mikel Landa, who began the day just 10 seconds off the race lead, jumped off the front of the overall contenders' group on an uncategorised climb with around 9 kilometres remaining. "That's the most important for now".
It will see riders undertake a 39.8km individual time trial from Foligno to Montefalco.