French 13th seed Kristina Mladenovic reached the third round with a comfortable 6-2 6-3 win against Sara Errani of Italy.
Back on court with the 12th-seeded Tsonga trailing 7-5, 6-4, 6-7 (6), 5-4, the Frenchman lasted less than eight minutes, losing the first three points on his serve but managing to save the three match points. "I knew that if I insisted with my strategy I could succeed", Muguruza said.
Earlier this year, she made the final on clay in Charleston, where she went down to Daria Kasatkina in the first all-teenage title match since 2009.
Carreno Busta had a solid run-up to the French Open, but he's taken it to another level in Paris - the high being point his third-round, straight-sets win over Grigor Dimitrov.
The Spaniard will meet Yulia Putintseva of Kazakhstan, the 27th seed, for a place in the fourth round. She played very well. "I mean, there were some moments, some close moments in the second set, where I felt like I could have done a better job", Kontaveit said.
"It was really hard for me a year ago", Nadal said. "I don't have words to describe the love I have for you and what you bring me". But Williams is too experienced and too focused on this excellent opportunity to add a French Open title to her dazzling resume to dwell on revenge fantasies.
In a game lasting just less than one hour, Goffin and Horacio Zeballos held their serve twice for a 2-2 tie, before Goffin's first break came in the fifth game.
Moreover, Putintseva continued to struggle as her backhand continued to break down as Muguruza regained her break advantage to lead 4-3.
Venus Williams is last on the main court, against Elise Mertens.