Fairley played the past six National Football League seasons with an enlarged heart, a condition diagnosed during a routine physical exam at the National Football League combine prior to the 2011 draft.
Fairley's play helped him earn a four-year, $28 million extension in March.
Fairley visited a cardiologist last month and since then has been away from OTAs and out of communication with many of his teammates. He racked up 6.5 sacks and 43 tackles. However, a doctor has said that his career should not continue, according to Saints head coach Sean Payton.
Fairley sometimes struggled to meet expectations during his first five pro seasons.
Fairley was a first-round pick by the Lions and spent four seasons in Detroit. Fairley had the best year of his career with the Saints.
On June 3, The Advocate's Nick Underhill reported that Fairley missed organized team activities because of a heart issue. The Saints and Fairley had been consulting with doctors how best to proceed with his medical situation.
In his career, Fairley has played in 77 regular-season games, making 170 solo or assisted tackles - including one safety - and 20½ sacks. They also have 2nd year DT David Onyemata and 3rd year DT Tyeler Davison. The New York Jets recently out Sheldon Richardson on the trade block, Richardson has been a solid player for the Jets but he has a character problem that might be too much for the Saints to go after him.